Type your tag names separated by a space and hit enter

Papanicolaou Smear

Papanicolaou Smear is a topic covered in the Davis's Lab & Diagnostic Tests.

To view the entire topic, please or purchase a subscription.

Nursing Central is the award-winning, complete mobile solution for nurses and students. Look up information on diseases, tests, and procedures; then consult the database with 5,000+ drugs or refer to 65,000+ dictionary terms. Explore these free sample topics:

Nursing Central

-- The first section of this topic is shown below --

General

Synonym/Acronym:
Pap smear, cervical smear.

Common Use:
To establish a cytological diagnosis of cervical and vaginal disease and identify the presence of genital infections, such as human papillomavirus, herpes, and cytomegalovirus.

Specimen:
Cervical and endocervical cells.

Normal Findings:
Method: (Microscopic examination of fixed and stained smear) Reporting of Pap smear findings may follow one of several formats and may vary by laboratory. Simplified content of the two most common formats for interpretation are listed in the table.

Bethesda System
    Specimen type:
  •  Smear, liquid-based, or other.
    Specimen adequacy:
  • Satisfactory for evaluation—endocervical transformation zone component is described as present or absent, along with other quality indicators (e.g., partially obscuring blood, inflammation).
  • Unsatisfactory for evaluation—either the specimen is rejected and the reason given or the specimen is processed and examined but not evaluated for epithelial abnormalities and the reason is given.
    General categorization:
  • Negative for intraepithelial lesion or malignancy.
  • Epithelial cell abnormality (abnormality is specified in the interpretation section of the report).
  • Other comments
    Interpretation/result:
  • Negative for intraepithelial lesion or malignancy
    • List organisms causing infection:
      • Trichomonas vaginalis; fungal organisms consistent with Candida spp.; shift in flora suggestive of bacterial vaginosis; bacteria morphologically consistent with Actinomyces spp.; cellular changes consistent with herpes simplex virus
    • Other nonneoplastic findings:
      • Reactive cellular changes associated with inflammation, radiation, intrauterine device; glandular cell status post-hysterectomy; atrophy.
  • Epithelial cell abnormalities
    • Squamous cell abnormalities
      • ASC of undetermined significance (ASC-US) cannot exclude HSIL (ASC-H)
      • LSIL encompassing HPV, mild dysplasia, CIN 1
      • HSIL encompassing moderate and severe dysplasia, CIS/CIN 2 and CIN 3 with features suspicious for invasion (if invasion is suspected)
      • Squamous cell carcinoma
    • Glandular cell
      • Atypical glandular cells (NOS or specify otherwise)
      • Atypical glandular cells, favor neoplastic (NOS or specify otherwise)
      • Endocervical adenocarcinoma in situ
      • Adenocarcinoma
  • Other
    • Endometrial cells (in a woman of 40 yr or greater)
    Automated review:
  • Indicates the case was examined by an automated device and the results are listed along with the name of the device.
    Ancillary testing:
  • Describes the test method and result.
    Educational notes and suggestions:
  • Should be consistent with clinical follow-up guidelines published by professional organizations with references included.
ASC = atypical squamous cells; ASC-H = high-grade atypical squamous cells; ASC-US = atypical squamous cells undetermined significance; CIN = cervical intraepithelial neoplasia; CIS = carcinoma in situ; HSIL = high-grade squamous intraepithelial lesion; LSIL = low-grade squamous intraepithelial lesion.

-- To view the remaining sections of this topic, please or purchase a subscription --

Citation

Bladh, Mickey Lynn., and Anne M. Van Leeuwen. "Papanicolaou Smear." Davis's Lab & Diagnostic Tests, 7th ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425228/all/Papanicolaou_Smear.
Bladh ML, Van Leeuwen AM. Papanicolaou Smear. Davis's Lab & Diagnostic Tests. 7th ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425228/all/Papanicolaou_Smear. Accessed April 21, 2019.
Bladh, M. L., & Van Leeuwen, A. M. (2017). Papanicolaou Smear. In Davis's Lab & Diagnostic Tests. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425228/all/Papanicolaou_Smear
Bladh ML, Van Leeuwen AM. Papanicolaou Smear [Internet]. In: Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2017. [cited 2019 April 21]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425228/all/Papanicolaou_Smear.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Papanicolaou Smear ID - 425228 A1 - Bladh,Mickey Lynn, AU - Van Leeuwen,Anne M, BT - Davis's Laboratory & Diagnostic Tests UR - https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425228/all/Papanicolaou_Smear PB - F.A. Davis Company ET - 7 DB - Nursing Central DP - Unbound Medicine ER -