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Red blood cell osmotic fragility, OF.
To assess the fragility of erythrocytes related to red blood cell lysis toward diagnosing diseases such as hemolytic anemia.
Whole blood collected in a green-top (heparin) tube and two peripheral blood smears.
(Method: Spectrophotometry) Hemolysis (unincubated) begins at 0.5% sodium chloride (NaCl) solution and is complete at 0.3% NaCl solution. Results are compared to a normal curve.
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Bladh, Mickey Lynn., and Anne M. Van Leeuwen. "Osmotic Fragility." Davis's Lab & Diagnostic Tests, 7th ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425288/all/Osmotic_Fragility.
Bladh ML, Van Leeuwen AM. Osmotic Fragility. Davis's Lab & Diagnostic Tests. 7th ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425288/all/Osmotic_Fragility. Accessed April 21, 2019.
Bladh, M. L., & Van Leeuwen, A. M. (2017). Osmotic Fragility. In Davis's Lab & Diagnostic Tests. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425288/all/Osmotic_Fragility
Bladh ML, Van Leeuwen AM. Osmotic Fragility [Internet]. In: Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2017. [cited 2019 April 21]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425288/all/Osmotic_Fragility.
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