Davis's Lab & Diagnostic Tests
Apolipoproteins: A, B, and E
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General
Synonym/Acronym:
Apo A (Apo A1), Apo B (Apo B100), and Apo E.
Rationale
To identify levels of circulating lipoprotein to evaluate the risk of coronary artery disease (CAD).
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction. However, if the test is ordered in conjunction with a lipid profile or triglyceride level, instruct the patient to abstain from food for 6 to 12 hr before specimen collection.
Normal Findings
Method: Immunonephelometry for Apo A and Apo B; polymerase chain reaction (PCR) with restriction length enzyme digestion and polyacrylamide gel electrophoresis for Apo E.
| Age | Conventional Units | SI Units (Conventional Units × 0.01) |
|---|---|---|
| Child | Greater than 120 mg/dL | Greater than 1.2 g/L |
| Adult | ||
| Male | Greater than or equal to 120 mg/dL | Greater than 1.2 g/L |
| Female | Greater than or equal to 140 mg/dL | Greater than 1.4 g/L |
| Age | Conventional Units | SI Units (Conventional Units × 0.01) |
|---|---|---|
| 2 yr–Adult | Less than 90 mg/dL | Less than 0.9 g/L |
Normal Apo E: Homozygous phenotype for e3/e3.
Critical Findings and Potential Interventions
N/A
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General
Synonym/Acronym:
Apo A (Apo A1), Apo B (Apo B100), and Apo E.
Rationale
To identify levels of circulating lipoprotein to evaluate the risk of coronary artery disease (CAD).
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction. However, if the test is ordered in conjunction with a lipid profile or triglyceride level, instruct the patient to abstain from food for 6 to 12 hr before specimen collection.
Normal Findings
Method: Immunonephelometry for Apo A and Apo B; polymerase chain reaction (PCR) with restriction length enzyme digestion and polyacrylamide gel electrophoresis for Apo E.
| Age | Conventional Units | SI Units (Conventional Units × 0.01) |
|---|---|---|
| Child | Greater than 120 mg/dL | Greater than 1.2 g/L |
| Adult | ||
| Male | Greater than or equal to 120 mg/dL | Greater than 1.2 g/L |
| Female | Greater than or equal to 140 mg/dL | Greater than 1.4 g/L |
| Age | Conventional Units | SI Units (Conventional Units × 0.01) |
|---|---|---|
| 2 yr–Adult | Less than 90 mg/dL | Less than 0.9 g/L |
Normal Apo E: Homozygous phenotype for e3/e3.
Critical Findings and Potential Interventions
N/A
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