Immunoglobulins A, D, E, G, and M

General

Synonym/Acronym:
IgA, IgD, IgG, IgM.

Rationale
To quantitate immunoglobulins A, D, G, and M as indicators of immune system function, to assist in the diagnosis of conditions that result in deficient or excessive production of immunoglobulins; to investigate immune system disorders such as multiple myeloma. To assess IgE levels in order to identify the presence of an allergic or inflammatory immune response.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Nephelometry for IgA, IgD, IgG, IgM; Fluorescent enzyme immunoassay for IgE.

AgeConventional Units
IgA (SI = CU × 0.01) IgG (SI = CU × 0.01) IgM (SI = CU × 0.01)
Newborn–2 yr2–126 mg/dL242–1,108 mg/dL21–215 mg/dL
3–4 yr14–212 mg/dL485–1,160 mg/dL26–155 mg/dL
5–9 yr52–226 mg/dL514–1,672 mg/dL26–188 mg/dL
10–14 yr42–345 mg/dL581–1,652 mg/dL47–252 mg/dL
15–18 yr60–349 mg/dL479–1,433 mg/dL26–232 mg/dL
18 yr–adult68–408 mg/dL768–1,632 mg/dL35–263 mg/dL
IgD (SI = CU × 10)
Less than 15 mg/dL
IgE Conventional and SI Units
Less than 1 yrLess than 35 kU/L
1–2 yrLess than 98 kU/L
3 yrLess than 200 kU/L
4–6 yrLess than 308 kU/L
7–8 yrLess than 404 kU/L
9–12 yrLess than 697 kU/L
13–15 yrLess than 630 kU/L
16–17 yrLess than 538 kU/L
18 yr and olderLess than 215 kU/L
Values vary by method and instrument.

Critical Findings and Potential Interventions
N/A

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