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Immunoglobulins A, D, E, G, and M

Immunoglobulins A, D, E, G, and M is a topic covered in the Davis's Lab & Diagnostic Tests.

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IgA, IgD, IgG, and IgM.

To quantitate immunoglobulins A, D, G, and M as indicators of immune system function, to assist in the diagnosis of conditions that result in deficient or excessive production of immunoglobulins; to investigate immune system disorders such as multiple myeloma. To assess IgE levels in order to identify the presence of an allergic or inflammatory immune response.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
Method: Nephelometry for IgA, IgD, IgG, and IgM. Immunoassay for IgE.

AgeConventional UnitsSI Units
IgA(Conventional Units × 0.01)
 Newborn1–4 mg/dL0.01–0.04 g/L
 1–9 mo2–80 mg/dL0.02–0.8 g/L
 10–12 mo15–90 mg/dL0.15–0.9 g/L
 2–3 yr18–150 mg/dL0.18–1.5 g/L
 4–5 yr25–160 mg/dL0.25–1.6 g/L
 6–8 yr35–200 mg/dL0.35–2 g/L
 9–12 yr45–250 mg/dL0.45–2.5 g/L
 Older than 12 yr40–350 mg/dL0.40–3.5 g/L
IgD(Conventional Units × 10)
 NewbornGreater than 2 mg/dLGreater than 20 mg/L
 AdultLess than 15 mg/dLLess than 150 mg/L
IgG(Conventional Units × 0.01)
 Newborn650–1,600 mg/dL6.5–16 g/L
 1–9 mo250–900 mg/dL2.5–9 g/L
 10–12 mo290–1,070 mg/dL2.9–10.7 g/L
 2–3 yr420–1,200 mg/dL4.2–12 g/L
 4–6 yr460–1,240 mg/dL4.6–12.4 g/L
 Greater than 6 yr650–1,600 mg/dL6.5–16 g/L
IgM(Conventional Units × 0.01)
 NewbornLess than 25 mg/dLLess than 0.25 g/L
 1–9 mo20–125 mg/dL0.2–1.25 g/L
 10–12 mo40–150 mg/dL0.4–1.5 g/L
 2–8 yr45–200 mg/dL0.45–2 g/L
 9–12 yr50–250 mg/dL0.5–2.5 g/L
 Greater than 12 yr50–300 mg/dL0.5–3 g/L
IgEConventional and SI Units
Less than 1 yrLess than 20 units/mL
2–4 yrLess than 85 units/mL
5–9 yrLess than 1500 units/mL
10 yr and olderLess than 160 units/mL
Values vary by method and instrument.

Critical Findings and Potential Interventions

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Bladh, Mickey Lynn., and Anne M. Van Leeuwen. "Immunoglobulins A, D, E, G, and M." Davis's Lab & Diagnostic Tests, 7th ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425371/4/Immunoglobulins_A_D_E_G_and_M.
Bladh ML, Van Leeuwen AM. Immunoglobulins A, D, E, G, and M. Davis's Lab & Diagnostic Tests. 7th ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425371/4/Immunoglobulins_A_D_E_G_and_M. Accessed June 20, 2019.
Bladh, M. L., & Van Leeuwen, A. M. (2017). Immunoglobulins A, D, E, G, and M. In Davis's Lab & Diagnostic Tests. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425371/4/Immunoglobulins_A_D_E_G_and_M
Bladh ML, Van Leeuwen AM. Immunoglobulins A, D, E, G, and M [Internet]. In: Davis's Lab & Diagnostic Tests. F.A. Davis Company; 2017. [cited 2019 June 20]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425371/4/Immunoglobulins_A_D_E_G_and_M.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Immunoglobulins A, D, E, G, and M ID - 425371 A1 - Bladh,Mickey Lynn, AU - Van Leeuwen,Anne M, BT - Davis's Laboratory & Diagnostic Tests UR - https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Lab-and-Diagnostic-Tests/425371/4/Immunoglobulins_A_D_E_G_and_M PB - F.A. Davis Company ET - 7 DB - Nursing Central DP - Unbound Medicine ER -