Antidiuretic Hormone
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General
Synonym/Acronym:
Vasopressin, arginine vasopressin hormone, ADH.
Common Use:
To evaluate disorders that affect urine concentration related to fluctuations of ADH secretion, such as diabetes insipidus.
Specimen:
Plasma collected in a lavender-top (EDTA) tube.
Normal Findings:
(Method: Radioimmunoassay)
| Age | Antidiuretic Hormone* | SI Units (Conventional Units × 0.923) | |||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neonates | Less than 1.5 pg/mL | Less than 1.4 pmol/L | |||||||||||||||||||||||||||||||||||||||
| 1 day–18 yr (normally hydrated) | 0.5–1.7 pg/mL | Less than 0.5–1.6 pmol/L | |||||||||||||||||||||||||||||||||||||||
| Adult (normally hydrated) | 1–5 pg/mL | 0.9–4.6 pmol/L | |||||||||||||||||||||||||||||||||||||||
| *Conventional units. | |||||||||||||||||||||||||||||||||||||||||
Recommendation
This test should be ordered and interpreted with results of a serum osmolality.
| Serum Osmolality* | Antidiuretic Hormone | SI Units (Conventional Units × 0.923) | |||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 270–280 mOsm/kg | Less than 1.5 pg/mL | Less than 1.4 pmol/L | |||||||||||||||||||||||||||||||||||||||
| 280–285 mOsm/kg | Less than 2.5 pg/mL | Less than 2.3 pmol/L | |||||||||||||||||||||||||||||||||||||||
| 285–290 mOsm/kg | 1–5 pg/mL | 0.9–4.6 pmol/L | |||||||||||||||||||||||||||||||||||||||
| 290–295 mOsm/kg | 2–7 pg/mL | 1.8–6.5 pmol/L | |||||||||||||||||||||||||||||||||||||||
| 295–300 mOsm/kg | 4–12 pg/mL | 3.7–11.1 pmol/L | |||||||||||||||||||||||||||||||||||||||
| *Conventional units. | |||||||||||||||||||||||||||||||||||||||||
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