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To assist in diagnosing bacterial infection and risk for developing sepsis.
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Method: Fluorescence immunoassay.
|Age||Conventional Units||SI Units (Conventional Units × 1)|
|Newborn||Less than 2 ng/mL||Less than 2 mcg/L|
|18–20 hr||Less than 20 ng/mL||Less than 20 mcg/L|
|48 hr||Less than 5 ng/mL||Less than 5 mcg/L|
|3 d–adult||Less than 0.1 ng/mL||Less than 0.1 mcg/L|
|Interpretation||Conventional Units||SI Units|
|Bacterial infection absent or highly unlikely||Less than 0.1 ng/mL||Less than 0.1 mcg/L|
|Bacterial infection possible, low risk for development of sepsis||Less than 0.5 ng/mL||Less than 0.5 mcg/L|
|Bacterial infection likely, development of sepsis is possible||0.5–2 ng/mL||0.5–2 mcg/L|
|Bacterial infection highly likely, high risk for development of sepsis||2.1–9.9 ng/mL or greater||2.1–9.9 mcg/L or greater|
|Bacterial infection severe, septic shock is probable||10 ng/mL or greater||10 mcg/L or greater|
|The value of individual levels or absolute cutoffs varies between facilities; many have adopted multivariate criteria for the evaluation and management of sepsis that may or may not include procalcitonin measurements.|
Critical Findings and Potential Interventions