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NBS, newborn metabolic screening, tests for inborn errors of metabolism, early hearing loss detection and intervention for newborns.
To evaluate newborns for congenital abnormalities, which may include hearing loss; identification of hemoglobin variants such as thalassemias and sickle cell anemia; presence of antibodies that would indicate an HIV infection; or metabolic disorders such as homocystinuria, maple syrup urine disease (MSUD), phenylketonuria (PKU), tyrosinuria, and unexplained physical or intellectual disabilities.
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Method: Thyroxine, TSH, and HIV—immunoassay; amino acids—tandem mass spectrometry; hemoglobin variants—electrophoresis.
|Neonates–3 days||Normal pure tone average of –10 to 15 dB|
|Thyroid-Stimulating Hormone (TSH)|
|Age||Conventional Units||SI Units (Conventional Units × 1)|
|Neonates–3 days||Less than 40 micro-international units/mL||Less than 40 milli-international units/L|
|Age||Conventional Units||SI Units (Conventional Units × 12.9)|
|Neonates–30 days||5.4–22.6 mcg/dL||69.7–291.5 nmol/L|
|Hemoglobinopathies||Normal Hemoglobin Pattern|
|Blood spot amino acid analysis||Normal findings. Numerous amino acids are evaluated by blood spot testing, and values vary by method and laboratory. The testing laboratory should be consulted for corresponding reference ranges.|
|Infectious disease||Normal Findings|
Critical Findings and Potential Interventions