Prion Disease Testing

Prion Disease Testing is a topic covered in the Davis's Lab & Diagnostic Tests.

To view the entire topic, please or purchase a subscription.

Nursing Central is the award-winning, complete mobile solution for nurses and students. Look up information on diseases, tests, and procedures; then consult the database with 5,000+ drugs or refer to 65,000+ dictionary terms. Explore these free sample topics:

Nursing Central

-- The first section of this topic is shown below --

Synonym/Acronym:
Transmissible spongiform encephalopathies, TSEs.

Rationale
Testing for prion diseases may be considered for patients with undiagnosed, rapidly progressive dementia.

Patient Preparation
There are no activity restrictions unless by medical direction. Follow the food, fluid, or medication instructions indicated in the individual studies.

Normal Findings
Negative biopsy, normal cerebrospinal fluid (CSF) protein levels, normal electroencephalogram (EEG), normal magnetic resonance imaging (MRI), normal neurologic examination.

  • No evidence of prion disease
  • Negative tonsillar biopsy (if variant Creutzfeldt-Jakob disease [vCJD] is being considered), as vCJD is the only type known to involve the lymph nodes, spleen, tonsil, and appendix. Note: A negative biopsy does not rule out vCJD.

Critical Findings and Potential Interventions
N/A

-- To view the remaining sections of this topic, please or purchase a subscription --