Lyme Disease Testing

General

Synonym/Acronym:
N/A

Rationale
To detect antibodies to the organism that causes Lyme disease.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.

Normal Findings
(Method: Enzyme immunoassay [EIA]) Negative (indicating antibodies to Borrelia burgdorferi not detected); positives are confirmed either by a U.S. Food and Drug Administration (FDA)–approved EIA test that has been cleared for use in the serodiagnosis of Lyme disease or by Western blot analysis (immunoblot). Immunoblot Negative (indicating insufficient number of bands detected). The criterion for interpretation of a positive immunoblot test requires the identification of at least five specific bands.

Critical Findings and Potential Interventions
Specific infectious organisms are required to be reported to local, state, and national departments of health. Lists of specific organisms may vary among facilities. State health departments provide information regarding reportable diseases, which can be accessed at each state health department website. The Centers for Disease Control and Prevention (CDC) provides information regarding national notifiable diseases at https://ndc .services.cdc.gov/search-results-year/.

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