Davis's Lab & Diagnostic Tests
Varicella Testing
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General
Synonym/Acronym:
Varicella-zoster antibodies, chickenpox, VZ.
Rationale
To assist in confirming a diagnosis of a current, recent, or past varicella-zoster infection (chickenpox or shingles).
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Normal Findings
Method: Enzyme Immunoassay.
| IgM | Interpretation | IgG | Interpretation |
|---|---|---|---|
| Negative | No significant level of detectable antibody | Negative | No significant level of detectable antibody; indicative of nonimmunity |
| Indeterminate | Equivocal results; retest in 7–14 days | Indeterminate | Equivocal results; retest in 7–14 days |
| Positive | Antibody detected; indicative of recent immunization, current or recent infection | Positive | Antibody detected; indicative of immunization, current, or past infection |
Critical Findings and Potential Interventions
Specific infectious organisms are required to be reported to local, state, and national departments of health. Lists of specific organisms may vary among facilities. State health departments provide information regarding reportable diseases, which can be accessed at each state health department Web site. The CDC provides information regarding national notifiable diseases at https://ndc.services.cdc.gov /search-results-year.
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General
Synonym/Acronym:
Varicella-zoster antibodies, chickenpox, VZ.
Rationale
To assist in confirming a diagnosis of a current, recent, or past varicella-zoster infection (chickenpox or shingles).
Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction.
Normal Findings
Method: Enzyme Immunoassay.
| IgM | Interpretation | IgG | Interpretation |
|---|---|---|---|
| Negative | No significant level of detectable antibody | Negative | No significant level of detectable antibody; indicative of nonimmunity |
| Indeterminate | Equivocal results; retest in 7–14 days | Indeterminate | Equivocal results; retest in 7–14 days |
| Positive | Antibody detected; indicative of recent immunization, current or recent infection | Positive | Antibody detected; indicative of immunization, current, or past infection |
Critical Findings and Potential Interventions
Specific infectious organisms are required to be reported to local, state, and national departments of health. Lists of specific organisms may vary among facilities. State health departments provide information regarding reportable diseases, which can be accessed at each state health department Web site. The CDC provides information regarding national notifiable diseases at https://ndc.services.cdc.gov /search-results-year.
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