Albumin, Urine and Albumin to Creatinine Ratio (ACR)

General

Synonym/Acronym:
Microalbumin, micral; ACR

Rationale
To assist in the identification and management of early diabetes in order to avoid or delay onset of diabetic associated kidney disease.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction. Either a random or a 24-hr urine collection may be ordered. As appropriate, provide the required urine collection container and specimen collection instructions.

Normal Findings
Method: Immunoturbidometry for albumin, spectrophotometry for Cr.

Albumin Creatinine Ratio (ACR)
Conventional UnitsSI Units (Conventional Units x 0.113)
NormalLess than 30 mg/g creatinineLess than 3.4 mg/mmol creatinine
Clinically significant albuminuria30–299 mg/g creatinine3.4–33.8 mg/mmol creatinine
Overt albuminuriaGreater than 300 mg/g creatinineGreater than or equal to 33.9 mg/mmol creatinine
Laboratory reports include the measured levels of random urine albumin and creatinine, and reporting units may vary between laboratories; reference ranges are often listed as "not established."

Critical Findings and Potential Interventions
N/A

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