Albumin, Urine and Albumin/Creatinine Ratio (ACR)

General

Synonym/Acronym:
ACR

Rationale
To assist in the identification and management of early diabetes in order to avoid or delay onset of diabetic-associated kidney disease.

Patient Preparation
There are no food, fluid, activity, or medication restrictions unless by medical direction. Either a random or a 24-hr urine collection may be ordered. As appropriate, provide the required urine collection container and specimen collection instructions.

Normal Findings
Method: Immunoturbidometry for albumin, spectrophotometry for Cr.

Albumin, Urine (Random) Conventional Units SI Units (Conventional Units × 0.113)
MaleLess than 17 mg/g creatinineLess than 1.9 mg/mmol creatinine
FemaleLess than 25 mg/g creatinineLess than 2.8 mg/mmol creatinine
Albumin/Creatinine Ratio (ACR) Conventional Units SI Units (Conventional Units × 0.113)
NormalLess than 30 mg/g creatinineLess than 3.4 mg/mmol creatinine
Clinically significant albuminuria30–299 mg/g creatinine3.4–33.8 mg/mmol creatinine
Overt albuminuriaGreater than 300 mg/g creatinineGreater than or equal to 33.9 mg/mmol creatinine
Laboratory reports include the measured levels of random urine albumin and creatinine, and reporting units may vary between laboratories; reference ranges are often listed as “not established.”

Critical Findings and Potential Interventions
N/A

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