Charcot-Marie-Tooth disease

(shar-kō″mă-rē″tooth′ )

[Charcot; Pierre Marie, Fr. neurologist, 1853-1940; Howard Henry Tooth, Brit. physician, 1856-1925]
ABBR: CMT Progressive neural atrophy of muscles supplied by the peroneal nerves. There are numerous variants of the disease: some are X-linked; others are autosomal recessive. In all versions there is a defect in the myelination of peripheral nerves, causing motor deficits (such as footdrop) and loss of sensation.
SYN: SEE: peroneal muscular atrophy

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