Allen-Doisy test

(al′ĕn-doy′sē)

[Edgar V. Allen, U.S. endocrinologist, 1892-1943; Edward Adelbert Doisy, U.S. biochemist and physiologist, 1893-1986]
A test used to determine estrogen content. A spayed mouse is injected with the material being tested. The appearance of cornified cells on a vaginal smear constitutes a positive reaction.