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Behçet syndrome, Behçet disease

(bā′sĕt, be-chet′)

[Hulusi Behçet, Turkish dermatologist, 1889-1948]
A rare, multisystem, chronic, recurrent disease of unknown cause, marked by ulceration of the mouth and genitalia and by uveitis. The central nervous system, blood vessels, joints, and intestinal tract may be involved. It is genetically associated with HLA-B51. The disease occurs worldwide but is most common in the eastern Mediterranean and eastern Asia, where it occurs mostly in young men and is a leading cause of blindness. In the western world, where the disease is less severe, it affects men twice as frequently as it does women but is not a leading cause of blindness. The period between attacks is irregular but may be as short as days or as long as years.

TREATMENT
Therapy depends on the severity of the clinical findings. Mild disease of skin and joints may be treated with topical steroids or nonsteroidal anti-inflammatory drugs. Involvement of the central nervous system or gastrointestinal tract may require high dose steroids or cytotoxic drugs, such as chlorambucil, cyclophosphamide, or methotrexate.

SEE: silk road disease

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Citation

Venes, Donald, editor. "Behçet Syndrome, Behçet Disease." Taber's Medical Dictionary, 23rd ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/744543/all/Behçet_syndrome__Behçet_disease.
Behçet syndrome, Behçet disease. In: Venes D, ed. Taber's Medical Dictionary. 23rd ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/744543/all/Behçet_syndrome__Behçet_disease. Accessed July 18, 2019.
Behçet syndrome, Behçet disease. (2017). In Venes, D. (Ed.), Taber's Medical Dictionary. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/744543/all/Behçet_syndrome__Behçet_disease
Behçet Syndrome, Behçet Disease [Internet]. In: Venes D, editors. Taber's Medical Dictionary. F.A. Davis Company; 2017. [cited 2019 July 18]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/744543/all/Behçet_syndrome__Behçet_disease.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Behçet syndrome, Behçet disease ID - 744543 ED - Venes,Donald, BT - Taber's Medical Dictionary UR - https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/744543/all/Behçet_syndrome__Behçet_disease PB - F.A. Davis Company ET - 23 DB - Nursing Central DP - Unbound Medicine ER -