(dar-yā′)

French dermatologist, 1856-1938.

Darier disease

A rare autosomal dominant skin disease characterized by numerous warty papules that merge into large plaques. The lesions often become infected and may have an offensive odor.
SYN: SEE: keratosis follicularis

Darier sign

The skin change produced when the skin lesion in urticaria pigmentosa is rubbed briskly. The area usually begins to itch and becomes raised and surrounded by erythema.
SEE: mastocytosis; SEE: urticaria pigmentosa