Charcot, Jean M.
Fr. neurologist, 1825-1893.
SEE: C. joint.
Weakening and destruction of the joints of the feet and/or ankles in patients with diabetic neuropathy. Although the bony destruction limits the ability of the patient to walk, it is often painless.
SYN: SEE: diabetic neuroarthropathy; SEE: diabetic osteoarthropathy; SEE: diabetic osteopathy
A type of diseased joint marked by hypermobility associated with tabes dorsalis, syringomyelia, or other conditions involving spinal cord disease or injury. Bone decalcification occurs on the joint surfaces, accompanied by bony overgrowth about the margins. Pain is usually absent although there are exceptions. Deformity and instability of the joint are characteristic.
SYN: SEE: C. arthropathy
1. The combination of nystagmus, intention tremor, and scanning speech. It is frequently associated with multiple sclerosis.
2. The combination of right upper quadrant abdominal pain, fever, and jaundice, a marker of cholangitis.