[L. laesio, a wound]
1. A circumscribed area of altered or diseased tissue.
2. An injury or wound.
3. A single infected patch in a skin disease.
Primary or initial lesions include macules, vesicles, blebs or bullae, chancres, pustules, papules, tubercles, wheals, and tumors. Secondary lesions are the result of primary lesions. They may be crusts, excoriations, fissures, pigmentations, scales, scars, and ulcers.
4. To form or make a lesion.
anal squamous intraepithelial lesion
ABBR: ASIL SEE: Anal intraepithelial neoplasia.
SEE: Bankart lesion
A lesion caused by or showing degeneration.
A pathological change such as an infection, tumor, or injury that causes the death of tissue or an organ.
SEE: Dieulafoy, Georges
A lesion spreading over a large area.
1. A brain lesion that discharges nervous impulses.
2. A lesion that discharges an exudate.
A lesion of a small definite area.
A lesion visible to the eye without the aid of a microscope.
high-grade squamous intraepithelial lesion
ABBR: HGSIL A premalignant squamous lesion, found on the Papanicolaou test, which may be moderate dysplasia, severe dysplasia, or carcinoma in situ.
Treatment requires removal or destruction of the affected cells, usually with loop electrosurgical excision procedure (LEEP) or ablation. Left untreated, HGSIL may progress to invasive cervical cancer.
SEE: Hill-Sachs lesion
A lesion affecting separate systems of the body.
initial lesion of syphilis
A lesion that stimulates or excites activity in the part of the body where it is situated.
SEE: Janeway lesion
A lesion of nervous system origin giving rise to local symptoms.
lower motor neuron lesion
An injury occurring in the anterior horn cells, nerve roots, or peripheral nervous system that results in diminished reflexes, flaccid paralysis, and atrophy of muscles.
low-grade squamous intraepithelial lesion
ABBR: LGSIL A cytological abnormality found in Papanicolaou tests (Pap tests) where there are early mild changes in the epithelial cells covering the outside of the cervix. Causes include infection with human papillomavirus, cervical trauma, or postmenopausal changes. Risk factors include intercourse with multiple sex partners or a partner with multiple sex partners, unprotected sex at a young age, history of sexually transmitted disease, and tobacco use. About 60% of LGSIL will spontaneously resolve. If left untreated, a small number of women eventually develop cervical cancer.
SEE: Molecular disease.
A lesion of the nerve endings.
The first lesion of a disease, esp. used in referring to chancre of syphilis.
SEE: Quilty lesion
reverse Hill-Sachs lesion
A lesion with an identifiable border that contrasts with the substance it encloses, e.g., a lesion with a surrounding tissue layer or radiographic margin.
A front-to-back tear of the upper rim of the glenoid labrum where the biceps tendon anchors to the labrum. Common causes include falling on an outstretched hand; forceful, heavy lifting, and repeated overhead motion, e.g., throwing overhand. SLAP is an acronym of superior labral (tear) from anterior to posterior.
SYN: SEE: SLAP tear
A lesion that has a definite volume and may encroach on nearby structures.
SEE: mass (1)
In blood banking and transfusion therapy, the biochemical and structural degradation of blood cells that occurs over time.
A lesion that causes a change in tissue.
A lesion confined to organs of common function.
A lesion resulting from poisons or toxins from microorganisms.
upper motor neuron lesion
Neurological damage to the corticospinal or pyramidal tract in the brain or spinal cord. This lesion results in hemiplegia, paraplegia, or quadriplegia, depending on its location and extent. Clinical signs include loss of voluntary movement, spasticity, sensory loss, and pathological reflexes.
A lesion of a blood vessel.