osteomalacia
(os″tē-ō-mă-lā′sh(ē-)ă)
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[osteo- + -malacia]
An abnormality of new bone formation (osteoid) causing bones to become increasingly soft, flexible, brittle, and deformed. An adult form of rickets, osteomalacia can also be traced to liver disease, cancer, or other ailments that inhibit the normal metabolism of vitamin D.
SEE: rickets
osteomalacic (os″tē-ō-mă-lā′sik)
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, adj. CAUSES
The disease is often caused by any of the many vitamin D-deficiency disorders or diseases in which there is resistance to the effect of vitamin D on the skeleton, or by deranged phosphorus metabolism, chronic kidney disease, or renal tubular acidosis (among other more rare illnesses).
SYMPTOMS AND SIGNS
Clinical findings include bone and joint pains, e.g., in the limbs, lumbar spine, thorax, and pelvis; fractures; anemia; impaired gait, and progressive weakness.
DIAGNOSIS
Affected bones have a classical appearance on radiological imaging.
TREATMENT
Ergocalciferol and calcium are given as nutritional supplements to patients with vitamin D-deficient diets.
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Citation
Venes, Donald, editor. "Osteomalacia." Taber's Medical Dictionary, 24th ed., F.A. Davis Company, 2021. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/osteomalacia.
Osteomalacia. In: Venes DD, ed. Taber's Medical Dictionary. F.A. Davis Company; 2021. https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/osteomalacia. Accessed November 2, 2024.
Osteomalacia. (2021). In Venes, D. (Ed.), Taber's Medical Dictionary (24th ed.). F.A. Davis Company. https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/osteomalacia
Osteomalacia [Internet]. In: Venes DD, editors. Taber's Medical Dictionary. F.A. Davis Company; 2021. [cited 2024 November 02]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/osteomalacia.
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