To hear audio pronunciation of this topic, purchase a subscription or log in.
[osteo- + -malacia]
An abnormality of new bone formation (osteoid) causing bones to become increasingly soft, flexible, brittle, and deformed. An adult form of rickets, osteomalacia can also be traced to liver disease, cancer, or other ailments that inhibit the normal metabolism of vitamin D.
To hear audio pronunciation of this topic, purchase a subscription or log in., adj.
The disease is often caused by any of the many vitamin D-deficiency disorders or diseases in which there is resistance to the effect of vitamin D on the skeleton, or by deranged phosphorus metabolism, chronic kidney disease, or renal tubular acidosis (among other more rare illnesses).
SYMPTOMS AND SIGNS
Clinical findings include bone and joint pains, e.g., in the limbs, lumbar spine, thorax, and pelvis; fractures; anemia; impaired gait, and progressive weakness.
Affected bones have a classical appearance on radiological imaging.
Ergocalciferol and calcium are given as nutritional supplements to patients with vitamin D-deficient diets.
There's more to see -- the rest of this topic is available only to subscribers.
Venes, Donald, editor. "Osteomalacia." Taber's Medical Dictionary, 24th ed., F.A. Davis Company, 2021. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/tumor_induced_osteomalacia.
Osteomalacia. In: Venes DD, ed. Taber's Medical Dictionary. F.A. Davis Company; 2021. https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/tumor_induced_osteomalacia. Accessed May 29, 2023.
Osteomalacia. (2021). In Venes, D. (Ed.), Taber's Medical Dictionary (24th ed.). F.A. Davis Company. https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/tumor_induced_osteomalacia
Osteomalacia [Internet]. In: Venes DD, editors. Taber's Medical Dictionary. F.A. Davis Company; 2021. [cited 2023 May 29]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/tumor_induced_osteomalacia.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - osteomalacia ID - 770141 ED - Venes,Donald, BT - Taber's Medical Dictionary UR - https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/tumor_induced_osteomalacia PB - F.A. Davis Company ET - 24 DB - Nursing Central DP - Unbound Medicine ER -