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[osteo- + -malacia] An abnormality of new bone formation (osteoid) causing bones to become increasingly soft, flexible, brittle, and deformed. An adult form of rickets, osteomalacia can also be traced to liver disease, cancer, or other ailments that inhibit the normal metabolism of vitamin D. SEE: rickets osteomalacic (os″tē-ō-mă-lā′sik ), adj.
CAUSES The disease is often caused by any of the many vitamin D-deficiency disorders or diseases in which there is resistance to the effect of vitamin D on the skeleton, or by deranged phosphorus metabolism, chronic kidney disease, or renal tubular acidosis (among other more rare illnesses).
SYMPTOMS AND SIGNS Clinical findings include bone and joint pains, e.g., in the limbs, lumbar spine, thorax, and pelvis; fractures; anemia; impaired gait, and progressive weakness.
DIAGNOSIS Affected bones have a classical appearance on radiological imaging.
TREATMENT Ergocalciferol and calcium are given as nutritional supplements to patients with vitamin D-deficient diets.
Venes, Donald, editor. "Osteomalacia." Taber's Medical Dictionary, 23rd ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/tumor_induced_osteomalacia.
Osteomalacia. In: Venes D, ed. Taber's Medical Dictionary. 23rd ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/tumor_induced_osteomalacia. Accessed December 10, 2019.
Osteomalacia. (2017). In Venes, D. (Ed.), Taber's Medical Dictionary. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/tumor_induced_osteomalacia
Osteomalacia [Internet]. In: Venes D, editors. Taber's Medical Dictionary. F.A. Davis Company; 2017. [cited 2019 December 10]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/tumor_induced_osteomalacia.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - osteomalacia
ID - 770141
ED - Venes,Donald,
BT - Taber's Medical Dictionary
UR - https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770141/all/tumor_induced_osteomalacia
PB - F.A. Davis Company
ET - 23
DB - Nursing Central
DP - Unbound Medicine