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vasculitis

vasculitis is a topic covered in the Taber's Medical Dictionary.

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(vas″kyŭ-līt′ĭs )

(vas″kyŭ-lit′ĭ-dēz″ )

pl. vasculitides [L. vasculum, small vessel + -itis]
Inflammation of blood vessels.
It is usually caused by deposition of antigen-antibody immune complexes or other immune-mediated events. Vasculitis due to immune complexes is seen in patients with systemic lupus erythematosus, rheumatoid arthritis, hepatitis B and C, serum sickness, and drug reactions. Vasculitis found in patients with inflammatory bowel disease, Wegener granulomatosis, graft rejection, polyarthritis nodosa, and temporal arteritis involves other immune-mediated processes. Vasculitis often affects the renal glomeruli, joints, cerebral vessels, testes, or respiratory system.

Vasculitis can affect large, medium-sized, and small blood vessels. When it is found in small blood vessels in the skin, characteristic rashes may be seen. Vasculitis is loosely classified by the size of the vessel involved. Takayasu and giant cell arteritis involve large arteries, including the aorta and carotids. Polyarteritis nodosa and Kawasaki disease involve medium-sized vessels; Wegener granulomatosis, Henoch-Schönlein purpura, and microscopic polyangiitis involve small vessels, particularly in the kidney and respiratory tract.
SYN: SEE: angiitis


VASCULITIS ; SEE: autoimmune disease; SEE: immune complex

SYMPTOMS
Although fever, pain, and malaise are common, the inflammatory changes of the blood vessels are seen primarily through the signs and symptoms associated with the organ or tissues involved. Vasculitis in superficial vessels may present as painful nodules. Inflammation of the glomerular capillaries of the kidney in small vessel vasculitis may produce glomerulonephritis and decreased renal function. When blood vessels of the respiratory tract are involved, pneumonitis, sinusitis, and ulceration of the nasopharynx may result. Involvement of vessels in the heart leads to coronary artery disease and aneurysms.

TREATMENT
Immunosuppressive therapy (with drugs such as cyclophosphamide and prednisone, or monoclonal antibodies such as rituximab) is used to treat most forms of autoimmune-mediated vasculitis.


VASCULITIS

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Citation

Venes, Donald, editor. "Vasculitis." Taber's Medical Dictionary, 23rd ed., F.A. Davis Company, 2017. Nursing Central, nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770729/all/livedoid_vasculitis.
Vasculitis. In: Venes D, ed. Taber's Medical Dictionary. 23rd ed. F.A. Davis Company; 2017. https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770729/all/livedoid_vasculitis. Accessed July 21, 2019.
Vasculitis. (2017). In Venes, D. (Ed.), Taber's Medical Dictionary. Available from https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770729/all/livedoid_vasculitis
Vasculitis [Internet]. In: Venes D, editors. Taber's Medical Dictionary. F.A. Davis Company; 2017. [cited 2019 July 21]. Available from: https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770729/all/livedoid_vasculitis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - vasculitis ID - 770729 ED - Venes,Donald, BT - Taber's Medical Dictionary UR - https://nursing.unboundmedicine.com/nursingcentral/view/Tabers-Dictionary/770729/all/livedoid_vasculitis PB - F.A. Davis Company ET - 23 DB - Nursing Central DP - Unbound Medicine ER -